Anticentromere antibody positive Sjögren's Syndrome: a retrospective descriptive analysis

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Anticentromere antibody positive Sjögren's Syndrome: a retrospective descriptive analysis

INTRODUCTION A subgroup of patients with primary Sjögren's Syndrome (SS) and positive anticentromere antibodies (ACA) were recognized as having features intermediate between SS and systemic sclerosis (SSc). Our goal was to describe this group clinically and serologically and define its tendency to evolve to full blown SSc. METHODS Among 535 patients with primary SS we identified 20 ACA positi...

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The influence of anti-cyclic citrullinated peptide on anticentromere antibody-positive rheumatoid arthritis patients

that anticentromere antibody (ACA)-positive primary Sjögren’s syndrome (SS) shows a clinical phenotype intermediate between ACA-negative SS and systemic sclerosis (SSc) [1]. In our past study investigating the clinical features of 62 patients with positive ACA, only one patient had typical CREST syndrome, 9 patients had Raynaud’s phenomenon (8 with sclerodactyly, telangiectasia or calcinosis), ...

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The influence of anti-cyclic citrullinated peptide on anticentromere antibody-positive rheumatoid arthritis patients: authors' response

regarding the infl uence of anti-cyclic citrullinated peptide (CCP) on anticentromere antibody (ACA)-positive patients suff er ing from rheumatoid arthritis (RA) [1]. Th eir fi ndings explore the eff ect of ACA positivity in a patient group diff erent from the cohort of primary Sjögren syndrome (SS) patients we chose to study [2]. Due to the diff erent study population and the retrospective nat...

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ژورنال

عنوان ژورنال: Arthritis Research & Therapy

سال: 2010

ISSN: 1478-6354

DOI: 10.1186/ar2958